Measuring “Waiting” Impulsivity in Substance Addictions and Binge Eating Disorder in a Novel Analogue of Rodent Serial Reaction Time Task

@inproceedings{Voon2014MeasuringI,
  title={Measuring “Waiting” Impulsivity in Substance Addictions and Binge Eating Disorder in a Novel Analogue of Rodent Serial Reaction Time Task},
  author={Valerie Voon and Michael A Irvine and Katherine L. Derbyshire and Yulia Worbe and Iris Lange and Sanja Abbott and Sharon Morein-Zamir and Robyn Dudley and Daniele Caprioli and Neil A. Harrison and J C Wood and Jeffrey W. Dalley and Edward T. Bullmore and Jon E Grant and Trevor W. Robbins},
  booktitle={Biological Psychiatry},
  year={2014}
}
BACKGROUND Premature responding is a form of motor impulsivity that preclinical evidence has shown to predict compulsive drug seeking but has not yet been studied in humans. We developed a novel translation of the task, based on the rodent 5-choice serial reaction time task, testing premature responding in disorders of drug and natural food rewards. METHODS Abstinent alcohol- (n = 30) and methamphetamine-dependent (n = 23) subjects, recreational cannabis users (n = 30), and obese subjects… CONTINUE READING
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