Measurements of birth defect prevalence: which is most useful as a comparator group for pharmaceutical pregnancy registries?

Abstract

Pharmaceutical pregnancy registries document birth defects and other complications reported in pregnancies exposed to specific medications or diseases. A baseline estimate of birth defect prevalence is necessary for comparison. To identify potential teratogenic signals, the pregnancy registry must have a comparator that most closely matches the exposed… (More)
DOI: 10.1002/bdra.20572

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