Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation

@inproceedings{Cohen2009MeasurementOT,
  title={Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation},
  author={Jeremy Cohen and Renae V Deans and Andrew J Dalley and Jeffrey Lipman and Michael S. Roberts and Balasubramanian Venkatesh},
  booktitle={Critical care},
  year={2009}
}
INTRODUCTION The assessment of adrenal function in critically ill patients is problematic, and there is evidence to suggest that measurement of tissue glucocorticoid activity may be more useful than estimation of plasma cortisol concentrations. Interstitial cortisol concentrations of cortisol represent the available pool of glucocorticoids able to enter the cell and bind to the glucocorticoid receptor. However the concentrations of plasma cortisol may not accurately reflect interstitial… CONTINUE READING

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