Measurement of the intracellular free calcium concentration in salamander rods

@article{McNaughton1986MeasurementOT,
  title={Measurement of the intracellular free calcium concentration in salamander rods},
  author={Peter A McNaughton and Luigi Cervetto and B. J. Nunn},
  journal={Nature},
  year={1986},
  volume={322},
  pages={261-263}
}
Measurement of the free calcium concentration within a photo-receptor outer segment has been considered an important aim since the proposal by Hagins and Yoshikami1,2 that the primary event in phototransduction is a release of Ca2+ inside the cell. More recent evidence3–6 has cast doubt on the calcium hypothesis, and the observations of Yau and Nakatani7 and Matthews et al.6 suggest that the internal Ca2+ concentration ([Ca2+]i) may decrease after a flash of light. In the present study we have… CONTINUE READING

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