Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed tomography and magnetic resonance imaging.

@article{McMahon2015MeasurementOT,
  title={Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed tomography and magnetic resonance imaging.},
  author={Paul J McMahon and David Panczykowski and John K. Yue and Ava M. Puccio and Tomoo Inoue and Marco Sorani and Hester F. Lingsma and Andrew I. R. Maas and Alex B. Valadka and Esther L. Yuh and Pratik Mukherjee and Geoffrey T. Manley and David O. Okonkwo},
  journal={Journal of neurotrauma},
  year={2015},
  volume={32 8},
  pages={527-33}
}
Glial fibrillary acidic protein and its breakdown products (GFAP-BDP) are brain-specific proteins released into serum as part of the pathophysiological response after traumatic brain injury (TBI). We performed a multi-center trial to validate and characterize the use of GFAP-BDP levels in the diagnosis of intracranial injury in a broad population of patients with a positive clinical screen for head injury. This multi-center, prospective, cohort study included patients 16-93 years of age… CONTINUE READING
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Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators

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