Measurement of the degree of coupled isotopic enrichment of different positions in an antibiotic peptide by NMR.

@article{Miller1997MeasurementOT,
  title={Measurement of the degree of coupled isotopic enrichment of different positions in an antibiotic peptide by NMR.},
  author={A. F. Miller and L. Egan and C. Townsend},
  journal={Journal of magnetic resonance},
  year={1997},
  volume={125 1},
  pages={
          120-31
        }
}
  • A. F. Miller, L. Egan, C. Townsend
  • Published 1997
  • Chemistry, Medicine
  • Journal of magnetic resonance
  • An experimental strategy for determining the extent to which multiply isotopically labeled fragments are incorporated intact into relatively complicated compounds of interest is presented. The NMR methods employed are based on isotope-filtered one-dimensional spectra and difference HSQC spectra incorporating a spin echo designed to report on the presence of a second NMR active isotope at a coupled site. They supplement existing methods for determining the extent of isotopic incorporation at… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    References

    SHOWING 1-10 OF 51 REFERENCES
    Field gradient techniques in NMR spectroscopy.
    • L. Kay
    • Chemistry, Medicine
    • Current opinion in structural biology
    • 1995
    • 56
    Improved spectral resolution in cosy 1H NMR spectra of proteins via double quantum filtering.
    • 2,039