Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell.

@article{Teng2010MeasurementOT,
  title={Measurement of the copy number of the master quorum-sensing regulator of a bacterial cell.},
  author={Shu-Wen Teng and Yufang Wang and Kimberly C Tu and Tao Long and Pankaj Mehta and Ned S. Wingreen and Bonnie L Bassler and Nai Phuan Ong},
  journal={Biophysical journal},
  year={2010},
  volume={98 9},
  pages={2024-31}
}
Quorum-sensing is the mechanism by which bacteria communicate and synchronize group behaviors. Quantitative information on parameters such as the copy number of particular quorum-sensing proteins should contribute strongly to understanding how the quorum-sensing network functions. Here, we show that the copy number of the master regulator protein LuxR in Vibrio harveyi can be determined in vivo by exploiting small-number fluctuations of the protein distribution when cells undergo division. When… CONTINUE READING

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