Measurement of skeletal muscle: laboratory and epidemiological methods.

  title={Measurement of skeletal muscle: laboratory and epidemiological methods.},
  author={Steven B. Heymsfield and Dympna Gallagher and Marjolein Visser and C{\'e}sar N{\'u}{\~n}ez and Zimian M Wang},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  volume={50 Spec No},
Despite skeletal muscle's central role in the pathogenesis of sarcopenia, measurement methods remain underinvestigated and inadequately validated. Our review indicates that skeletal muscle (SM) measurement methods quantify different components and properties of muscle, ranging from the atomic to whole-body levels of body composition. Laboratory methods tend to measure whole body SM (e.g., total muscle protein, muscle cell mass, and adipose tissue-free SM components) while epidemiological… CONTINUE READING