Measurement of serum creatinine--current status and future goals.

  title={Measurement of serum creatinine--current status and future goals.},
  author={Michael J. Peake and Malcolm Whiting},
  journal={The Clinical biochemist. Reviews},
  volume={27 4},
The first methods for the measurement of creatinine in serum and plasma were published over a century ago. Today, the Jaffe reaction using alkaline picrate remains the cornerstone of most current routine methods, after continuous refinements attempting to overcome inherent analytical interferences and limitations. With the recent introduction of the reporting of estimated glomerular filtration rate (eGFR), inter-laboratory agreement of serum creatinine results has become an important… CONTINUE READING
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