Measurement of regional cerebral plasma pool and hematocrit with copper-62-labeled HSA-DTS.

@article{Okazawa1996MeasurementOR,
  title={Measurement of regional cerebral plasma pool and hematocrit with copper-62-labeled HSA-DTS.},
  author={Hitohi Okazawa and Yoshiharu Yonekura and Yasuhisa Fujibayashi and Hiroshi Yamauchi and Koichi Ishizu and Sadahiko Nishizawa and Yasuhiro Magata and N. Tamaki and Hidenao Fukuyama and Akira Yokoyama and J. Konishi},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1996},
  volume={37 7},
  pages={1080-5}
}
UNLABELLED We developed copper-62-labeled human serum albumin-dithiosemicarbazone (62Cu-HSA-DTS) as a blood-pool imaging agent for PET. To evaluate 62Cu-HSA-DTS for plasma-pool imaging and to measure the regional cerebral hematocrit, 12 normal volunteers and 7 patients with cerebrovascular disease underwent PET studies with 62Cu-HSA-DTS and 15O-labeled carbon monoxide (C15O). METHODS The normal subjects were studied with both C15O and 62Cu-HSA-DTS. All patients were examined by 15O-gas… CONTINUE READING

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