Measurement of particle size distribution in mammalian cells in vitro by use of polarized light spectroscopy.

Abstract

We demonstrate the feasibility of measuring the particle size distribution (PSD) of internal cell structures in vitro. We use polarized light spectroscopy to probe the internal morphology of mammalian breast cancer (MCF7) and cervical cancer (Siha) cells. We find that graphing the least-squared error versus the scatterer size provides insight into cell… (More)

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@article{Bartlett2004MeasurementOP, title={Measurement of particle size distribution in mammalian cells in vitro by use of polarized light spectroscopy.}, author={Matthew Bartlett and George T-J Huang and Lyndon L. Larcom and Huabei Jiang}, journal={Applied optics}, year={2004}, volume={43 6}, pages={1296-307} }