Measurement of parainfluenza-3 virus antibody by the single radial hemolysis technique.


A single radial hemolysis assay for parainfluenza-3 virus antibody is described as a simple, sensitive, accurate, and precise alternative to hemagglutination inhibition and serum neutralization tests. A highly significant correlation exists between single radial hemolysis zone areas and hemagglutination inhibition titers of both serum and nasal secretion samples. Antibody conversions equivalent to as little as a twofold rise in hemagglutination inhibition titer are readily and reliably detected in sera and nasal secretions. Single radial hemolysis and hemagglutination inhibition activity was demonstrable in the immunoglobulin G fraction of a hyperimmune parainfluenza-3 virus antiserum.

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@article{Probert1975MeasurementOP, title={Measurement of parainfluenza-3 virus antibody by the single radial hemolysis technique.}, author={M I Probert and Sarah M. Russell}, journal={Journal of clinical microbiology}, year={1975}, volume={2 3}, pages={157-61} }