Measurement of oxidation in plasma Lp(a) in CAPD patients using a novel ELISA.

@article{Podrez1998MeasurementOO,
  title={Measurement of oxidation in plasma Lp(a) in CAPD patients using a novel ELISA.},
  author={Eugene A. Podrez and June O'Neil and Robert G Salomon and Martin J. Schreiber and Henry F. Hoff},
  journal={Kidney international},
  year={1998},
  volume={54 2},
  pages={637-45}
}
BACKGROUND LGE2 is produced by the cyclooxygenase- or free radical-mediated modification of arachidonate and is formed during the oxidation of low density lipoprotein (LDL) with subsequent adduction to lysine residues in apo B. We have developed a sensitive enzyme-linked sandwich immunosorbent assay (ELISA) for detection and measurement of LGE2-protein adducts as an estimate of oxidation of plasma LDL and Lp(a). METHODS The assay employs rabbit polyclonal antibodies directed against LGE2… CONTINUE READING