Measurement of optical path length for cerebral near-infrared spectroscopy in newborn infants.

@article{Wyatt1990MeasurementOO,
  title={Measurement of optical path length for cerebral near-infrared spectroscopy in newborn infants.},
  author={John A. Wyatt and Michele Cope and David T. Delpy and P. Van Der Zee and Simon R. Arridge and Anthony David Edwards and E O R Reynolds},
  journal={Developmental neuroscience},
  year={1990},
  volume={12 2},
  pages={140-4}
}
The time taken for an extremely short pulse of near-infrared laser light to traverse the heads of 6 preterm infants was measured after death. The values obtained were used to calculate a differential path length factor (DPF), defined as the mean distance travelled by the photons divided by the distance between the points where light entered and left the head. The DPF was found to be 4.39 +/- 0.28. Knowledge of this factor will permit accurate quantitative measurements to be made by near… CONTINUE READING

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