Measurement of optic nerve blood flow with nonradioactive colored microspheres in rabbits.

@article{Orgl1996MeasurementOO,
  title={Measurement of optic nerve blood flow with nonradioactive colored microspheres in rabbits.},
  author={Selim Org{\"u}l and George A. Cioffi and David R. Bacon and Anuja Bhandari and E Michael Van Buskirk},
  journal={Microvascular research},
  year={1996},
  volume={51 2},
  pages={
          175-86
        }
}
The objective of this study was to establish a nonradioactive technique to accurately assess blood flow in a small tissue such as the anterior optic nerve. Colored microspheres, 10.2 +/- 0.23 microns in diameter, were injected into the left atrium in each of 17 anesthetized rabbits. The rabbits were divided into four groups injected, respectively, with 5, 10, 50, or 100 million microspheres. Microsphere quantification in the tissue was performed after postmortem dissection and alkaline… CONTINUE READING
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