Measurement of myocardial fatty acid metabolism: kinetics of iodine-123 heptadecanoic acid in normal dog hearts.

@article{Schoen1986MeasurementOM,
  title={Measurement of myocardial fatty acid metabolism: kinetics of iodine-123 heptadecanoic acid in normal dog hearts.},
  author={H{\'e}l{\`e}ne Schoen and Reingard Senekowitsch and Dieter Berg and Martin Schneidereit and G{\"u}nther Reidel and Heinz Kriegel and Hans Pabst and Hans Bl{\"o}mer},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1986},
  volume={27 9},
  pages={1449-55}
}
To define the potential of iodine-123 heptadecanoic acid (IHA) for the noninvasive assessment of myocardial fatty acid metabolism with gamma camera imaging, the influence of myocardial oxygen consumption (MVO2) and blood flow (MBF) on extraction and half-times of IHA were investigated in dogs. Following IHA injection into the left circumflex coronary artery, extraction fraction and half-times were derived from the peak and slope of the IHA time activity curve, which consisted of a vascular… CONTINUE READING
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