Measurement of mouse brain glucose utilization in vivo using [U-14C]glucose

@article{Kamp1980MeasurementOM,
  title={Measurement of mouse brain glucose utilization in vivo using [U-14C]glucose},
  author={Cylia W. Kamp and D. A. Mursch and William B. Stavinoha and Miguel {\'A}ngel Medina},
  journal={Neurochemical Research},
  year={1980},
  volume={5},
  pages={61-67}
}
The rate of [2-14C]glucose uptake has been used as an indication of the status of energy consumption by the rat brain, but the cost of this radiolabel can be prohibitive and the surgical manipulation involved in published methods is extensive. A method for measuring glucose utilization in vivo in mouse brain with [U-14C]glucose is described in this article. Glucose consumption in whole mouse brain obtained with [U-14C]glucose or [2-14C]glucose was 0.650±0.022 and 0.716±0.36 nmol/mg/min… CONTINUE READING
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