Measurement of microstructural strain in cortical bone.

  title={Measurement of microstructural strain in cortical bone.},
  author={Daniel P Nicolella and Lynda F. Bonewald and Donald E Moravits and James Lankford},
  journal={European journal of morphology},
  volume={42 1-2},
It is well known that mechanical factors affect bone remodeling such that increased mechanical demand results in net bone formation, whereas decreased demand results in net bone resorption. Current theories suggest that bone modeling and remodeling is controlled at the cellular level through signals mediated by osteocytes. The objective of this study was to investigate how macroscopically applied bone strains similar in magnitude to those that occur in vivo are manifest at the microscopic level… CONTINUE READING

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