Measurement of low-dose active pharmaceutical ingredient in a pharmaceutical blend using frequency-domain photon migration.

@article{Pan2004MeasurementOL,
  title={Measurement of low-dose active pharmaceutical ingredient in a pharmaceutical blend using frequency-domain photon migration.},
  author={Tianshu Pan and Don Barber and David Coffin-Beach and Zhigang Sun and Eva M. Sevick-Muraca},
  journal={Journal of pharmaceutical sciences},
  year={2004},
  volume={93 3},
  pages={635-45}
}
Frequency-domain photon migration (FDPM) measurements of time-dependent light propagation are conducted to provide the powder absorbance for quantitative prediction of terazosin as the active pharmaceutical ingredient (API) in a low-dose (0.72 wt %) oral tablet formulation. Calibration of the FDPM-derived powder absorbance at discrete wavelengths of 514… CONTINUE READING