Measurement of lipid peroxidation in vivo: A comparison of different procedures

  title={Measurement of lipid peroxidation in vivo: A comparison of different procedures},
  author={Alfonso Pompella and Emilia Maellaro and A Casini and Marco Ferrali and Lucia Ciccoli and Mario Comporti},
A study was undertaken to investigate whether some of the methods commonly used to detect lipid peroxidation of cellular membranes in vivo correlate with each other. The study was performed with the livers of bromobenzene-intoxicated mice, in which lipid peroxidation develops when the depletion of glutathione (GSH) reaches a threshold value. The methods tested and compared were the following: i) measurement of the malondialdehyde (MDA) content of the liver; ii) detection of diene conjugation… CONTINUE READING
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