Measurement of iron status in chronic kidney disease

  title={Measurement of iron status in chronic kidney disease},
  author={Wesley Hayes},
  journal={Pediatric Nephrology (Berlin, Germany)},
  pages={605 - 613}
  • Wesley Hayes
  • Published 2018
  • Medicine
  • Pediatric Nephrology (Berlin, Germany)
  • Anemia is a common complication of chronic kidney disease (CKD) in children, and dysregulation of iron homeostasis plays a central role in its pathogenesis. Optimizing iron status is a prerequisite for effective treatment of anemia. Insufficient iron can lead to inappropriate escalation of the erythropoiesis-stimulating agent (ESA) dose, which is associated with adverse outcomes. Excess iron supplementation also has negative sequelae including free radical tissue damage and increased risk of… CONTINUE READING
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