Measurement of human high density lipoprotein apolipoprotein A-1 in serum by radioimmunoassay.

@article{Karlin1976MeasurementOH,
  title={Measurement of human high density lipoprotein apolipoprotein A-1 in serum by radioimmunoassay.},
  author={J B Karlin and D J Juhn and J I Starr and Angelo M. Scanu and Arthur H. Rubenstein},
  journal={Journal of lipid research},
  year={1976},
  volume={17 1},
  pages={30-7}
}
A sensitive and specific double antibody radioimmunoassay for the major apolipoprotein (apo A-I) of human serum high density lipoprotein (HDL) was developed. Initial studies indicated that direct measurements of apo A-I concentration in whole untreated sera or isolated high density lipoprotein fractions yielded variable results, which were lower than those obtained in the corresponding samples which had been subjected to delipidation. Subsequently, it was observed that heating diluted sera or… CONTINUE READING

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