Measurement of hippocampal atrophy using 4D graph-cut segmentation: Application to ADNI

  title={Measurement of hippocampal atrophy using 4D graph-cut segmentation: Application to ADNI},
  author={Robin Wolz and Rolf A. Heckemann and Paul Aljabar and Joseph V. Hajnal and Alexander Hammers and Jyrki L{\"o}tj{\"o}nen and Daniel Rueckert},
  volume={52 1},
We propose a new method of measuring atrophy of brain structures by simultaneously segmenting longitudinal magnetic resonance (MR) images. In this approach a 4D graph is used to represent the longitudinal data: edges are weighted based on spatial and intensity priors and connect spatially and temporally neighboring voxels represented by vertices in the graph. Solving the min-cut/max-flow problem on this graph yields the segmentation for all timepoints in a single step. By segmenting all… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
71 Citations
47 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 71 extracted citations


Publications referenced by this paper.
Showing 1-10 of 47 references

A meta-analysis of hippocampal atrophy rates in Alzheimer's disease

  • J. Barnes, J. W. Bartlett, +5 authors N. C. Fox
  • Neurobiol. Aging
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…