Measurement of fibrinolytic activity after epsilon-aminocaproic acid administration in rats (Rattus norvegicus).


The antifibrinolytic agent, epsilon-aminocaproic acid was administered to rats via either intraperitoneal injection or intravenous infusion. Time-response and dose-response studies of the resultant plasma levels of fibrinolytic activity were measured by a modification of a standard fibrin plate technique. The modified technique involved the addition of… (More)


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