Measurement of eight urinary metabolites of di(2-ethylhexyl) phthalate as biomarkers for human exposure assessment.

@article{Silva2006MeasurementOE,
  title={Measurement of eight urinary metabolites of di(2-ethylhexyl) phthalate as biomarkers for human exposure assessment.},
  author={Manori J. Silva and John A. Reidy and James L. Preau and Ella Samandar and Larry L Grandjean Needham and Antonia M. Calafat},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={2006},
  volume={11 1},
  pages={1-13}
}
Human metabolism of di(2-ethylhexyl) phthalate (DEHP) is complex and yields mono(2-ethylhexyl) phthalate (MEHP) and numerous oxidative metabolites. The oxidative metabolites, mono(2-ethyl-5-oxohexyl) phthalate (MEOHP), mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), mono(2-ethyl-5-carboxypentyl) phthalate (MECPP) and mono(2-carboxymethylhexyl) phthalate (MCMHP), have been considered to be better biomarkers for DEHP exposure assessment than MEHP because urinary levels of these metabolites are… CONTINUE READING

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