Measurement of drug agglomerates in powder blending simulation samples by near infrared chemical imaging.

Abstract

This research note describes a powder blending simulation study conducted using 20-mL scintillation vials and a bench-top rotating mixer on a scale of 2g for each sample. In order to investigate the impact of mean particle size and size distribution on blending behavior of an active pharmaceutical ingredient (API), the drug substance was separated into… (More)

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