Measurement of diffusion coefficients of parabens and steroids in water and 1-octanol.

Abstract

Diffusion coefficients (D) of parabens and steroids in water and 1-octanol were determined by using the chromatographic broadening method at 37 degrees C, and the relationships between the D values and the physicochemical properties of the drugs were discussed. The D values in 1-octanol were lower than those in water because of the higher viscosity of 1… (More)

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@article{Seki2003MeasurementOD, title={Measurement of diffusion coefficients of parabens and steroids in water and 1-octanol.}, author={Toshinobu Seki and Junko Mochida and Maiko Okamoto and Osamu Hosoya and Kazuhiko Juni and Kazuhiro Morimoto}, journal={Chemical & pharmaceutical bulletin}, year={2003}, volume={51 6}, pages={734-6} }