Measurement of canine IgE using the alpha chain of the human high affinity IgE receptor.

@article{Stedman2001MeasurementOC,
  title={Measurement of canine IgE using the alpha chain of the human high affinity IgE receptor.},
  author={Kim Stedman and K Lee and Shirley W Hunter and Bernard Rivoire and Catherine McCall and Donald L. Wassom},
  journal={Veterinary immunology and immunopathology},
  year={2001},
  volume={78 3-4},
  pages={349-55}
}
In vitro assays for allergen specific immunoglobulin E (IgE) are a convenient and reproducible alternative to intradermal skin testing in dogs. Such tests may be used to support a diagnosis of atopic dermatitis and to define appropriate allergens for immunotherapy. Current in vitro assays rely upon monoclonal or polyclonal antibodies as IgE detection reagents. However, in sera where allergen-specific IgG occurs in great excess, any IgE:IgG cross-reactivity of the detection reagent may result in… CONTINUE READING