Measurement of brain pH using 11CO2 and positron emission tomography.

Abstract

We have examined the feasibility of measuring local brain pH in vivo with 11CO2 and positron emission tomography. In particular, we have addressed two objections that have been raised against this method: the assumed need to estimate local tissue PCO2 and the rapid fixation of 11C in tissue. From a reexamination of the basic theory, we argue that after… (More)

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Cite this paper

@article{Buxton1984MeasurementOB, title={Measurement of brain pH using 11CO2 and positron emission tomography.}, author={Richard B. Buxton and Lawrence R. Wechsler and Nadelon Alpert and Robert H. Ackerman and David R. Elmaleh and J de A Correia}, journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism}, year={1984}, volume={4 1}, pages={8-16} }