Measurement of bone morphogenetic proteins and other growth factors in demineralized bone matrix.

@article{Blum2004MeasurementOB,
  title={Measurement of bone morphogenetic proteins and other growth factors in demineralized bone matrix.},
  author={Barbara E Blum and Jon Moseley and Leasa Miller and Kelly C Richelsoph and Warren O. Haggard},
  journal={Orthopedics},
  year={2004},
  volume={27 1 Suppl},
  pages={s161-5}
}
Osteoinductivity of demineralized bone matrix has been attributed to bone morphogenetic proteins (BMP). Other growth factors, including insulin-like growth factor-1 (IGF-1) and transforming growth factor-beta1 (TGF-beta1), have also been detected in demineralized bone matrix. Success of bone graft substitutes containing demineralized bone matrix has been assumed to be closely associated with osteoinductivity of the demineralized bone matrix. Because of differences in bone characteristics… CONTINUE READING
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