Measurement of axonal membrane conductances and capacity by means of a varying potential control voltage clamp

@article{Palti1969MeasurementOA,
  title={Measurement of axonal membrane conductances and capacity by means of a varying potential control voltage clamp},
  author={Yoram Palti and William J. Adelman},
  journal={The Journal of Membrane Biology},
  year={1969},
  volume={1},
  pages={431-458}
}
A new mode of voltage clamping in the squid giant axon is introduced and its advantages are analyzed, tested, and utilized to investigate membrane conductances and capacity. This method replaces the constant command potentials of the standard voltage clamp with potentials which vary with time. Some of the advantages in using the varying potential clamp are: (1) slowly varying potentials generate practically pureI K ; (2) rapidly varying potentials generate practically pureI Na; (3) triangular… CONTINUE READING

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