Measurement of autolysis in submerged batch cultures of Penicillium chrysogenum.

@article{McNeil1998MeasurementOA,
  title={Measurement of autolysis in submerged batch cultures of Penicillium chrysogenum.},
  author={B. Wayne McNeil and David R. Berry and Linda M. Harvey and Alexander Grant and Stewart White},
  journal={Biotechnology and bioengineering},
  year={1998},
  volume={57 3},
  pages={297-305}
}
The process of cellular autolysis was studied in an industrial strain of Penicillium chrysogenum by a range of methods, including assessment of biomass decline, NH+4 release, changes in culture apparent viscosity, and by means of a quantitative assessment of changes in micromorphology using a computerized image analysis system. The pattern of total intracellular proteolytic and beta-1, 3-glucanolytic activity in the culture was also examined. The overall aim was to identify a suitable method… CONTINUE READING