Measurement of apoptosis.

@article{Darzynkiewicz1998MeasurementOA,
  title={Measurement of apoptosis.},
  author={Zbigniew Darzynkiewicz and Frank Traganos},
  journal={Advances in biochemical engineering/biotechnology},
  year={1998},
  volume={62},
  pages={33-73}
}
The cell dying by apoptosis undergoes a sequence of morphological, biochemical, and molecular changes which are characteristic, and often unique, to this mode of cell death. Specific features of apoptotic cells resulting from these changes, which serve as markers used to reveal the apoptotic mode of cell death and to quantify the extent of apoptosis in cultures or in tissue, are reviewed. Analysis of these features by flow or image cytometry is the most commonly used approach to detect… CONTINUE READING

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