Measurement of airway mucosal perfusion and water volume with an inert soluble gas.

@article{Wanner1988MeasurementOA,
  title={Measurement of airway mucosal perfusion and water volume with an inert soluble gas.},
  author={Adam Wanner and J A Barker and William M. Long and Andrej T. Mariassy and Alejandro D. Chediak},
  journal={Journal of applied physiology},
  year={1988},
  volume={65 1},
  pages={264-71}
}
The purpose of this study was to develop and validate a new in vivo technique for the measurement of tracheal mucosal blood flow (Qtr) and tissue water volume (VH2O) with an inert soluble gas. The technique was based on the notion that the uptake of dimethyl ether (VDME) from an isolated tracheal segment is governed by VH2O (transient state) and Qtr (steady state). In lightly anesthetized sheep, an endotracheal tube with two cuffs placed 14.5-16.5 cm apart was placed to create a chamber into… CONTINUE READING

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