Measurement of Total Malondialdehyde in Plasma and Tissues by High-Performance Liquid Chromatography and Thiobarbituric Acid Assay

@inproceedings{TKZKAN2006MeasurementOT,
  title={Measurement of Total Malondialdehyde in Plasma and Tissues by High-Performance Liquid Chromatography and Thiobarbituric Acid Assay},
  author={Nurten T{\"U}K{\"O}ZKAN and H{\"u}samettin Erdamar},
  year={2006}
}
Objective: Malondialdehyde, a product of lipid peroxidation, is a good marker for development of oxidative stress. Mateials and Methods: In this study MDA was determined in the tissues and plasma by means of thiobarbituric acid test and directly by reverse phase high-pressure liquid chromatography method after derivatisation with 2,4-dinitrophenylhidrazine. Results: We have found a significant difference between two methods by Mann-Whitney U test (p<0.001). There was the formation of non… CONTINUE READING
Highly Cited
This paper has 19 citations. REVIEW CITATIONS