Measurement of IGF-1, IGFBP-3 and free IGF-1 levels by ELISA in growth hormone (GH) deficient children before and after GH replacement.

@article{Wacharasindhu2002MeasurementOI,
  title={Measurement of IGF-1, IGFBP-3 and free IGF-1 levels by ELISA in growth hormone (GH) deficient children before and after GH replacement.},
  author={Suttipong Wacharasindhu and Suphab Aroonparkmongkol and Sumarlee Srivuthana},
  journal={Asian Pacific journal of allergy and immunology},
  year={2002},
  volume={20 3},
  pages={155-60}
}
Serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) levels reflect the growth hormone (GH) status. A few percent of IGF-1 circulate in a free form which is believed to represent the IGF biological activity. We retrospectively studied the changes of serum IGF-1, serum IGFBP-3, and plasma free IGF-1 levels in growth hormone deficient (GHD) children before and after treatment with recombinant human growth hormone (rhGH) for a period of 6 months and… CONTINUE READING