Measurement of H 2 AX Phosphorylation as a Marker of Ionizing Radiation Induced Cell Damage

@inproceedings{Muslimovi2012MeasurementOH,
  title={Measurement of H 2 AX Phosphorylation as a Marker of Ionizing Radiation Induced Cell Damage},
  author={Aida Muslimovi{\'c} and Pegah Johansson and Ola Hammarsten},
  year={2012}
}
Cancer therapy often involves drugs or radiation, which induce DNA double-strand breaks (DSBs) and cause death of tumor cells. A dilemma with radiation and chemotherapy is the narrow therapeutic window and the fact that the sensitivity to DNA damage varies greatly in the human population, resulting in severe side effects and therapy-related deaths. Radiation and chemotherapy are usually planned during 1-3 weeks and delivered over a period of weeks to months. DNA damage testing of the patient… CONTINUE READING
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Highly Influential
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  • Aida Muslimovic, Pegah Johansson, Ola Hammarsten
  • Mitsuru Nenoi (Ed.),
  • 2012

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