Measurement and simulation of noninactivating Ca current in smooth muscle cells.

  title={Measurement and simulation of noninactivating Ca current in smooth muscle cells.},
  author={Yuji Imaizumi and Katsuhiko Muraki and Masae Takeda and Masaru Watanabe},
  journal={The American journal of physiology},
  volume={256 4 Pt 1},
An attempt was made to obtain electrophysiological evidence for continuous influx of Ca ion through voltage-dependent Ca channel (VDCC) in smooth muscle during long depolarization, for example in high K solution. Noninactivated Ca current [ICa(ni)] remaining after the accomplishment of voltage-dependent inactivation by prolonged depolarization for approximately 1 min was detected by three means under whole cell voltage clamp in several types of smooth muscle cells. The measurement of ICa(ni… CONTINUE READING

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