Measurement and modeling of nitric oxide release rates for nitric oxide donors.

@article{Ramamurthi1997MeasurementAM,
  title={Measurement and modeling of nitric oxide release rates for nitric oxide donors.},
  author={Anand Ramamurthi and Randy S. Lewis},
  journal={Chemical research in toxicology},
  year={1997},
  volume={10 4},
  pages={408-13}
}
An accurate model of the nitric oxide (NO)-release rate is essential for predicting the temporal NO-release rate and resulting NO concentrations for NO donors. Knowledge of the NO-release rate and/or the NO concentration is beneficial for assessing the physiological or pathological effects of NO on cell systems. This study describes a method to measure the temporal NO-release rate from NO donor compounds utilizing a modified ultrafiltration cell. For this study, the NO-release rates of spermine… CONTINUE READING
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