Measurement and clinical effect of grey matter pathology in multiple sclerosis

@article{Geurts2012MeasurementAC,
  title={Measurement and clinical effect of grey matter pathology in multiple sclerosis},
  author={Jeroen Geurts and Massimiliano Calabrese and Elizabeth H. Fisher and Richard A. Rudick},
  journal={The Lancet Neurology},
  year={2012},
  volume={11},
  pages={1082-1092}
}
During the past 10 years, the intense involvement of the grey matter of the CNS in the pathology of multiple sclerosis has become evident. On gross inspection, demyelination in the grey matter is rather inconspicuous, and lesions in the grey matter are mostly undetectable with traditional MRI sequences. However, the results of immunohistochemical studies have shown extensive involvement of grey matter, and researchers have developed and applied new MRI acquisition methods as a result. Imaging… CONTINUE READING
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