Measles virus replication in lungs of hispid cotton rats after intranasal inoculation.

@article{Wyde1992MeaslesVR,
  title={Measles virus replication in lungs of hispid cotton rats after intranasal inoculation.},
  author={Philip R. Wyde and Marie Ambrose and Thomas G. Voss and Hans-Dieter Meyer and Brian E. Gilbert},
  journal={Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine},
  year={1992},
  volume={201 1},
  pages={80-7}
}
Hispid cotton rats were inoculated intranasally with either measles virus (MV) Edmonston, a multipassaged, tissue culture-adapted strain of MV, or with one of three clinical MV isolates that had limited passages (three to five times) in tissue culture cells. MV Edmonston was recovered from the lungs of every (n = 37) hispid cotton rat inoculated with this virus for at least 7 days after virus inoculation. Peak pulmonary titers occurred on Day +4 (3.3-4.4 log10/g lung). Scattered areas of… CONTINUE READING

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