Measles Virus RNA in Tonsils of Asymptomatic Children

@article{Anlar2002MeaslesVR,
  title={Measles Virus RNA in Tonsils of Asymptomatic Children},
  author={Banu Anlar and Ayşe Ayhan and Hak Hotta and Masae Itoh and Durgun Engin and Saha Dalal Barun and {\"O}. K{\"o}seoğlu},
  journal={Journal of Paediatrics and Child Health},
  year={2002},
  volume={38}
}
Hepatitis G virus/GB virus C (HGV/GBV-C) is a blood-borne flavivirus of humans that was first characterized in 1995. While up to 80% of acutely infected individuals spontaneously clear the virus, chronic viraemia is common and can persist for up to 16 years. 1 The production of antibodies to the HGV/GBV-C envelope protein E2 has been associated with the clearance of the virus and is believed to protect against reinfection. 2 In communities in developed countries, HGV/GBV-C has a high prevalence… 
High Rates of Detection of Respiratory Viruses in Tonsillar Tissues from Children with Chronic Adenotonsillar Disease
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Respiratory viruses are highly prevalent in adenoids and palatine tonsils of patients with chronic tonsillar diseases, and persistence of these viruses in tonsils may stimulate chronic inflammation and play a role in the pathogenesis of these diseases.
Measles Lymphadenopathy in a Child With PFAPA Syndrome
  • J. Terry, K. Brown, L. Tucker
  • Medicine, Biology
    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • 2018
TLDR
Measles-type viral cytopathic effect was discovered on histological examination of tonsillar tissue after therapeutic tonsillectomy for PFAPA, and molecular testing showed the left tonsil was positive for measles RNA by reverse transcription polymerase chain reaction (RT-PCR) while the righttonsil was inconclusive (weakly positive).
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Treatment with inosiplex and interferons may induce temporary stabilization or remission in about 30–35 % of the cases and immunization against measles virus and maintenance of immunization rates above 90 % in the population are of extreme importance for the prevention of these debilitating or fatal disorders.
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