Measles Outbreaks in a Population with Declining Vaccine Uptake

  title={Measles Outbreaks in a Population with Declining Vaccine Uptake},
  author={Vincent A. A. Jansen and Nico Stollenwerk and Harold James Jensen and Mary E Ramsay and W. John Edmunds and Christopher J. Rhodes},
  pages={804 - 804}
Measles is a highly infectious and potentially dangerous disease. Before mass vaccination was started in the United Kingdom, measles caused an average of 100 deaths per year ( [1][1] ). Since the introduction of vaccination, vaccine uptake has risen from around 50% in 1968 to 76% in 1988. After the 

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Global measles elimination

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Measles and the importance of maintaining vaccination levels.

People with measles are usually infectious for one to two days before the rash appears but the total period during which an individual is infectious is not known.

Measles vaccination in an increasingly immunized and developed world

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    Human vaccines & immunotherapeutics
  • 2019
Why countries with high immunization coverage are still threatened by measles outbreaks and how changing dynamics may alter disease control are highlighted.

A Measles Epidemic Threshold in a Highly Vaccinated Population

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The impact of Australia's measles control programme over the past decade

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    Epidemiology and Infection
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Australia is making good progress towards measles elimination, but as in other countries, this progress can be sustained only by maintaining high vaccination coverage with the routine childhood vaccination schedule.

Measles Control and the Prospect of Eradication

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  • Medicine
    Current topics in microbiology and immunology
  • 2009
Global measles eradication will face a number of challenges to achieving and sustaining high levels of vaccine coverage and population immunity, including population growth and demographic changes, conflict and political instability, and public perceptions of vaccine safety.

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A limited measles outbreak in U.S.-born children living in a military community in Germany after vaccine refusal and other vaccination delays.

This report summarizes an outbreak of measles among five unvaccinated children living in a U.S. military community in Wiesbaden, Germany, in March to April of 2004. The index case was a 3-year-old



Interpretation of serological surveillance data for measles using mathematical models: implications for vaccine strategy

Serological surveillance of measles immunity in England has been carried out in England since 1986/7 and showed that there was cause for concern over the levels of susceptibility to measles, with an epidemic of over 100000 cases likely in 1995/6.

Power laws governing epidemics in isolated populations

Measurements of the distribution of epidemic sizes and duration are used to show that regularities in the dynamics of such systems do become apparent and that the observed power-law exponents are well described by a simple lattice-based model which reflects the social interaction between individual hosts.

A simple model for complex dynamical transitions in epidemics.

This work has shown that measles is a natural ecological system that exhibits different dynamical transitions at different times and places, yet all of these transitions can be predicted as bifurcations of a single nonlinear model.

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See and public/sb0218.htm for National Health Service immunization statistics [cited 15

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Methods are available as supporting material at Science online

  • Methods are available as supporting material at Science online

J. Theor. Biol

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