Mean-field methods in evolutionary duplication-innovation-loss models for the genome-level repertoire of protein domains.

@article{Angelini2010MeanfieldMI,
  title={Mean-field methods in evolutionary duplication-innovation-loss models for the genome-level repertoire of protein domains.},
  author={Annalisa Angelini and Alberto Amato and Ginestra Bianconi and Bruno Bassetti and Marco Cosentino Lagomarsino},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2010},
  volume={81 2 Pt 1},
  pages={
          021919
        }
}
We present a combined mean-field and simulation approach to different models describing the dynamics of classes formed by elements that can appear, disappear, or copy themselves. These models, related to a paradigm duplication-innovation model known as Chinese restaurant process, are devised to reproduce the scaling behavior observed in the genome-wide repertoire of protein domains of all known species. In view of these data, we discuss the qualitative and quantitative differences of the… CONTINUE READING

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