Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes

@inproceedings{Beisswenger2011MealinducedII,
  title={Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes},
  author={Paul J. Beisswenger and William Virgil Brown and Antonio Ceriello and Ngoc-Anh Le and R. Goldberg and John P Cooke and David C. Robbins and Samiha Sarwat and Hongbo Yuan and Cate A. Jones and Meng H. Tan},
  booktitle={Diabetic medicine : a journal of the British Diabetic Association},
  year={2011}
}
AIM To determine if a regimen with prandial + basal insulin compared with basal insulin attenuates post-meal inflammatory and glycative biomarkers in patients with Type 2 diabetes. METHODS This test-meal sub-study in the USA is from a previously reported clinical trial comparing the effect on glycaemic control of 24 weeks of thrice-daily pre-meal insulin lispro mix 50 (50% insulin lispro, 50% insulin lispro protamine suspension) or bedtime insulin glargine, both plus metformin. In the sub… CONTINUE READING
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