Meal-Related Increases in Vascular Reactivity are Impaired in Older and Diabetic Adults - Insights into the Roles of Aging and Insulin in Vascular Flow


A fatty meal induces vasodilatation (of both resting and stimulated forearm flow) in healthy young adults, an effect most likely mediated by the vasodilator actions of insulin. We therefore hypothesized that an impaired meal-related vascular response might be an “in vivo” marker of vascular insulin resistance, related to the presence of diabetes and/or… (More)


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