Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis.

@article{Lei1997Mcm2IA,
  title={Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis.},
  author={Ming Lei and Yasuo Kawasaki and Michael R. Young and Maki Kihara and Akio Sugino and Bik K. Tye},
  journal={Genes & development},
  year={1997},
  volume={11 24},
  pages={3365-74}
}
The initiation of DNA synthesis is an important cell cycle event that defines the beginning of S phase. This critical event involves the participation of proteins whose functions are regulated by cyclin dependent protein kinases (Cdks). The Mcm2-7 proteins are a family of six conserved proteins that are essential for the initiation of DNA synthesis in all eukaryotes. In Saccharomyces cerevisiae, members of the Mcm2-7 family undergo cell cycle-specific phosphorylation. Phosphorylation of Mcm… CONTINUE READING