Mcm10 is required for oogenesis and early embryogenesis in Drosophila

@article{Reubens2015Mcm10IR,
  title={Mcm10 is required for oogenesis and early embryogenesis in Drosophila},
  author={Michael C. Reubens and Megan D. Biller and Sidney E. Bedsole and Lucas T. Hopkins and Elizabeth T Ables and Tim W. Christensen},
  journal={Mechanisms of Development},
  year={2015},
  volume={138},
  pages={291-299}
}
Efficient replication of the genome and the establishment of endogenous chromatin states are processes that are essential to eukaryotic life. It is well documented that Mcm10 is intimately linked to both of these important biological processes; therefore, it is not surprising that Mcm10 is commonly misregulated in many human cancers. Most of the research regarding the biological roles of Mcm10 has been performed in single-cell or cell-free in-vitro systems. Though these systems are informative… CONTINUE READING
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