Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching.

@article{Wu1998Mcm1RD,
  title={Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching.},
  author={Chundren Wu and Kh Weiss and Chien-chih Yang and Murray A. Harris and Bik K. Tye and Carol S Newlon and R. T. Simpson and James E Haber},
  journal={Genes & development},
  year={1998},
  volume={12 11},
  pages={
          1726-37
        }
}
Switching of Saccharomyces mating type by replacement of sequences at the MAT locus involves a choice between two donors, HML and HMR. MATalpha cells inhibit recombination along the entire left arm of chromosome III, including HML, whereas MATa cells activate this same region. MATa-dependent activation of HML depends on a small, cis-acting DNA sequence designated the recombination enhancer (RE), located 17 kb centromere-proximal to HML. A comparison of RE sequences interchangeable between… CONTINUE READING
BETA

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

Similar Papers

Loading similar papers…