MazF6 toxin of Mycobacterium tuberculosis demonstrates antitoxin specificity and is coupled to regulation of cell growth by a Soj-like protein

@inproceedings{Ramrez2013MazF6TO,
  title={MazF6 toxin of Mycobacterium tuberculosis demonstrates antitoxin specificity and is coupled to regulation of cell growth by a Soj-like protein},
  author={M. V. Micca Ram{\'i}rez and Clinton C. Dawson and Rebecca M Crew and Kathleen England and Richard A. Slayden},
  booktitle={BMC Microbiology},
  year={2013}
}
BackgroundMolecular programs employed by Mycobacterium tuberculosis (Mtb) for the establishment of non-replicating persistence (NRP) are poorly understood. In order to investigate mechanisms regulating entry into NRP, we asked how cell cycle regulation is linked to downstream adaptations that ultimately result in NRP. Based on previous reports and our recent studies, we reason that, in order to establish NRP, cells are halted in the cell cycle at the point of septum formation by coupled… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 53 REFERENCES

Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2013
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